Your Brain Might be Genetically Built to Hold On to Stress Too Long.
Before You Buy -
Watch My 5-Minute Breakdown
There’s a good chance your COMT gene is slowing your brain’s ability to clear dopamine, adrenaline, and estrogen.
If your nervous system feels like it’s always on edge, you may be dealing with a genetic variant called Slow COMT.
You can genetically fix your:
✗ Insomnia that doesn’t respond to sleep supplements ✗ Brain fog that gets worse with “detox” or B vitamins ✗ Racing thoughts at night—even when you’re exhausted ✗ Anxiety spikes from small stressors or social interaction ✗ Overthinking or inability to turn your brain off ✗ Feeling tired but wired all day ✗ Emotional overreactions you can’t seem to stop ✗ Sensitivity to sound, light, conflict, or overstimulation ✗ Feeling worse after taking methylfolate or SAMe ✗ Short fuse, irritability, or “snapping” under pressure ✗ Strong stress responses after caffeine, noise, or supplements ✗ Panic, adrenaline surges, or shakiness without clear cause ✗ Waking in the middle of the night with a racing heart ✗ Feeling mentally fragile even after trying magnesium or adaptogens
“Since I began supplementing using your Roadmap, I’ve made significant gains in both sleep and calmness of mind.”
— Roadmap Purchaser, via email
This clinically-tested protocol helps you calm your system without overwhelming it. Designed specifically for people with Slow COMT variants—but even if you don’t know your genetics, the symptoms will tell you.
Wired Brain? Start Fixing It in 3 Minutes with my FREE
Cheat Sheet
It gives you:
The most important supplements to take—including dosages and exact timing,
The most important foods to eat,
Medications and supplements that commonly make things worse for slow COMT types.
“Here is a good first step up to this particular fountain of knowledge.”
— Cheat Sheet Reviewer
This Roadmap Is Designed Specifically For You.
I work regularly with people who have:
Sleep that never feels restorative
Racing thoughts or sudden surges of panic
Crashes after brief bursts of motivation or focus
Worsening symptoms from B-complexes, folate, or methyl donors
Constant sensitivity to supplements, caffeine, or stress
Unrelenting brain fog—even with a “healthy” diet
If this sounds like you, there’s a quite high chance your COMT gene is the missing piece.
Read my highly popular, in-depth articles on Slow COMT:
Or start with the Slow COMT Cheat Sheet if you want one clear page of directly actionable info:
The Clinical-Grade Roadmap Includes:
A close distillation of the exact clinical protocol I use with patients who have failed multiple supplement plans, still feel overstimulated, or can't sleep despite “doing everything right”
A 4-phase sequence designed to stabilize your biochemical framework first then repair neurotransmitter balance, not the other way around (In my opinion, many of my patients fail other protocols due to this problem).
Targeted supplement strategies for stabilizing dopamine, methylation, and stress hormones, based entirely on COMT clearance physiology
Nutritional, lifestyle, and lab-based tools to fix what’s driving symptoms rather than masking them
Delivered as a professional-grade PDF for instant access, lifetime use, no logins or subscriptions
~ Dr. Malek
Why I Built This
I’m a licensed MD who has worked with literally hundreds of people with slow COMT function.
Almost everything out there on COMT is—with all due respect—either oversimplified, overhyped, or (quite frankly) flat-out wrong.
Most protocols ignore sequence, ignore physiology, and end up overstimulating the very people they’re supposed to help. I’ve written this Roadmap because there is nothing else out there like it.
Based on my experience: This actually works.
Get the Roadmap:
Get immediate access to the full clinical-grade roadmap
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“I’m already feeling less anxious after starting just the tier 1 and tier 2 supplements.”
— Roadmapper, via video call
If the roadmap doesn’t help you, please do email me. I am extremely responsive and will help you personally.
If you’re not ready for the full protocol:
Get my free Slow COMT Cheat Sheet, which gives you:
The most important supplements to take and avoid, with dosages and direct links,
The most important foods to eat,
Medications to avoid.
Slow COMT function affects how the brain and body clear dopamine, norepinephrine, and estrogen—contributing to anxiety, fatigue, supplement intolerance, and poor sleep. This guide explains the full range of symptoms, why they’re often missed, and what works to stabilize those biochemical pathways.